{"response":{"docs":[{"system_create_dtsi":"2018-05-10T15:13:19Z","system_modified_dtsi":"2019-06-06T15:04:40Z","has_model_ssim":["StudentWork"],"id":"ng451h930","accessControl_ssim":["a50576c9-9a1d-4e8d-9785-d71c454b2e9a"],"hasRelatedMediaFragment_ssim":["hd76s038s"],"hasRelatedImage_ssim":["hd76s038s"],"depositor_ssim":["jallaqsr@mail.uc.edu"],"depositor_tesim":["jallaqsr@mail.uc.edu"],"title_tesim":["Hematopoietic Development of iPSC Derived Human Liver Organoids"],"date_uploaded_dtsi":"2018-05-10T15:12:25Z","date_modified_dtsi":"2019-05-23T15:10:10Z","isPartOf_ssim":["admin_set/default"],"doi_tesim":["doi:10.7945/C2TT37"],"geo_subject_tesim":["Cincinnati, Ohio"],"advisor_tesim":["Takebe, Takanori"],"degree_tesim":["BS Biology"],"college_tesim":["Arts and Sciences"],"department_tesim":["Takebe Research Lab: Department of Gastroenterology, Hepatology and Nutrition | Cincinnati Children's Hospital Medical Center"],"genre_tesim":["Poster"],"creator_tesim":["Lewis, Kyle","Jallaq, Sahar","Takebe, Takanori"],"publisher_tesim":["University of Cincinnati"],"subject_tesim":["Biology"],"language_tesim":["English"],"description_tesim":["Human iPSCs (TkDA cell-line) were differentiated on laminin coated plates into endoderm by treatment of Activin and BMP, then treated with FGF4 and CHIR to further differentiate into posterior foregut.  The cells were embedded into Matrigel droplets and cultured in Advanced DMEM. Droplet media was collected for ELISA to measure Albumin concentrations.  The droplets were collected for histology and RNA isolation to test for AFP, ALB, and HBG1 genes.  These methods resulted in the creation of a novel culture system containing both hepatic and hematopoietic lineage cells to model developing fetal liver."],"license_tesim":["http://rightsstatements.org/vocab/InC/1.0/"],"date_created_tesim":["2018-04"],"thumbnail_path_ss":"/downloads/hd76s038s?file=thumbnail","suppressed_bsi":false,"actionable_workflow_roles_ssim":["admin_set/default-default-depositing"],"workflow_state_name_ssim":["deposited"],"member_ids_ssim":["hd76s038s"],"file_set_ids_ssim":["hd76s038s"],"visibility_ssi":"open","admin_set_tesim":["Default Admin Set"],"sort_title_ssi":"HEMATOPOIETIC DEVELOPMENT OF IPSC DERIVED HUMAN LIVER ORGANOIDS","human_readable_type_tesim":["Student Work"],"read_access_group_ssim":["public"],"edit_access_person_ssim":["jallaqsr@mail.uc.edu"],"nesting_collection__pathnames_ssim":["ng451h930"],"nesting_collection__deepest_nested_depth_isi":1,"_version_":1697084426578558976,"timestamp":"2021-04-15T05:50:30.401Z","score":0.00049999997}],"facets":[{"name":"human_readable_type_sim","items":[{"value":"Student Work","hits":1,"label":"Student Work"}],"label":"Human Readable Type Sim"},{"name":"creator_sim","items":[{"value":"Jallaq, Sahar","hits":1,"label":"Jallaq, Sahar"},{"value":"Lewis, Kyle","hits":1,"label":"Lewis, Kyle"},{"value":"Takebe, Takanori","hits":1,"label":"Takebe, Takanori"}],"label":"Creator Sim"},{"name":"subject_sim","items":[{"value":"Biology","hits":1,"label":"Biology"}],"label":"Subject Sim"},{"name":"college_sim","items":[{"value":"Arts and Sciences","hits":1,"label":"Arts and Sciences"}],"label":"College Sim"},{"name":"department_sim","items":[{"value":"Takebe Research Lab: Department of Gastroenterology, Hepatology and Nutrition | Cincinnati Children's Hospital Medical Center","hits":1,"label":"Takebe Research Lab: Department of Gastroenterology, Hepatology and Nutrition | Cincinnati Children's Hospital Medical Center"}],"label":"Department Sim"},{"name":"language_sim","items":[{"value":"English","hits":1,"label":"English"}],"label":"Language Sim"},{"name":"publisher_sim","items":[{"value":"University of Cincinnati","hits":1,"label":"University of Cincinnati"}],"label":"Publisher Sim"},{"name":"date_created_sim","items":[{"value":"2018-04","hits":1,"label":"2018-04"}],"label":"Date Created Sim"},{"name":"member_of_collection_ids_ssim","items":[],"label":"Member Of Collection Ids Ssim"},{"name":"generic_type_sim","items":[{"value":"Work","hits":1,"label":"Work"}],"label":"Generic Type Sim"}],"pages":{"current_page":1,"next_page":null,"prev_page":null,"total_pages":1,"limit_value":10,"offset_value":0,"total_count":1,"first_page?":true,"last_page?":true}}}