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  • Real-time control of radiofrequency ablation using three-dimensional ultrasound echo decorrelation imaging in normal and diseased ex vivo human liver

    Dataset thumbnail: Real-time control of radiofrequency ablation using three-dimensional ultrasound echo decorrelation imaging in normal and diseased ex vivo human liver
    Type:
    Dataset
    Description/Abstract:
    This data set contains ultrasound image, tissue ablation. and temperature data measured in the study reported in the article: Real-time control of radiofrequency ablation using three-dimensional ultrasound echo decorrelation imaging in normal and diseased ex vivo human liver Elmira Ghahramani, Peter D Grimm, Benjamin E Weiss, Nicholas S Schoenleb, Alexander J Knapp, Jiang Wang, Syed A Ahmad, Shimul A Shah, Ralph C Quillin III, Sameer H Patel Physics in Medicine and Biology, 2025  https://iopscience.iop.org/article/10.1088/1361-6560/adaacb To best understand and use this data set, please refer to this article. Files in the data set include: Annotated Excel spreadsheet containing summary data for all 109 trials in this study (12 preliminary trials, followed by 97 primary trials; see spreadsheet for variable listing): ExVivoHumanLiver_RFA_Decorrelation_SummaryData.xlsx CSV spreadsheet containing the same summary data without annotations: ExVivoHumanLiver_RFA_Decorrelation_SummaryData.csv MATLAB data file (version 7) containing the same summary data, within the structure variable 'summary': ExVivoHumanLiver_RFA_Decorrelation_SummaryData.mat Example MATLAB script demonstrating reading and some analysis of results from all trials, with PDF of code and its output: ExVivoHumanLiver_RFA_Decorrelation_ExampleScript.m ExVivoHumanLiver_RFA_Decorrelation_ExampleScript.pdf MATLAB data files (version 7) containing results from each trial: ExVivoHumanLiver_RFA_Decorrelation_RawData_Trial1.mat through ExVivoHumanLiver_RFA_Decorrelation_RawData_Trial109.mat. Each of these files contains the structure variable "rawdata", containing the following fields for each trial: segmented_ablation_zone: 60x60x60 logical array (step size 1 mm) of segmented liver tissue map (1=ablated, 0=unablated). Dimensions are (z,y,x) as defined in Ghahramani et al. (2025), with z being range from the transducer surface (horizontal in room coordinates), y the azimuthal array direction (horizontal in room coordinates), and x the elevational array direction (vertical in room coordinates). The RFA probe was placed with its tip approximately at the center of this volume, with its needle parallel to the x axis. IQ_echo_data: 60x60x60x2xN complex array containing beamformed, demodulated IQ (in-phase/quadrature) echo data interpolated onto the same grid. The array of echo volumes comprises N pairs (one pair acquired every 22 s), with the two volumes from each pair separated by the inter-frame time of 50 ms. instantaneous_decorrelation: 60x60x60xN real array containing echo decorrelation per ms (linear scale) computed for each frame pair, using the equation and methods from section 2.3 in Ghahramani et al. (2025). thermocouple_locations: 4x3 real array (same for each trial), with each row comprising the (z,y,x) coordinates (voxel indices within the 60x60x60 grid) of a corresponding thermocouple integrated into the RFA probe. thermocouple_temperatures: 4xM real array, with each row comprising the measured temperatures (degrees C) measured during ablation, synchronous with the last M ultrasound IQ and decorrelation frames of each trial (not available for trials 30, 78, 91, and 102-109). decorrelation_at_thermocouples: 4xM real array, with each row comprising the measured decorrelation per ms (linear scale) at each thermocouple location, synchronous with the last M ultrasound IQ and decorrelation frames of each trial.
    Creator/Author:
    Mast, T. Douglas
    Submitter:
    T. Douglas Mast
    Date Uploaded:
    02/04/2025
    Date Modified:
    06/04/2025
    Date Created:
    2025
    License:
    Attribution 4.0 International