This data set contains ultrasound image, tissue ablation. and temperature data measured in the study reported in the article:
Real-time control of radiofrequency ablation using three-dimensional ultrasound echo decorrelation imaging in normal and diseased ex vivo human liver
Elmira Ghahramani, Peter D Grimm, Benjamin E Weiss, Nicholas S Schoenleb, Alexander J Knapp, Jiang Wang, Syed A Ahmad, Shimul A Shah, Ralph C Quillin III, Sameer H Patel
Physics in Medicine and Biology, 2025
https://iopscience.iop.org/article/10.1088/1361-6560/adaacb
To best understand and use this data set, please refer to this article.
Files in the data set include:
Annotated Excel spreadsheet containing summary data for all 109 trials in this study (12 preliminary trials, followed by 97 primary trials; see spreadsheet for variable listing):
ExVivoHumanLiver_RFA_Decorrelation_SummaryData.xlsx
CSV spreadsheet containing the same summary data without annotations:
ExVivoHumanLiver_RFA_Decorrelation_SummaryData.csv
MATLAB data file (version 7) containing the same summary data, within the structure variable 'summary':
ExVivoHumanLiver_RFA_Decorrelation_SummaryData.mat
Example MATLAB script demonstrating reading and some analysis of results from all trials, with PDF of code and its output:
ExVivoHumanLiver_RFA_Decorrelation_ExampleScript.m
ExVivoHumanLiver_RFA_Decorrelation_ExampleScript.pdf
MATLAB data files (version 7) containing results from each trial:
ExVivoHumanLiver_RFA_Decorrelation_RawData_Trial1.mat through ExVivoHumanLiver_RFA_Decorrelation_RawData_Trial109.mat.
Each of these files contains the structure variable "rawdata", containing the following fields for each trial:
segmented_ablation_zone:
60x60x60 logical array (step size 1 mm) of segmented liver tissue map (1=ablated, 0=unablated). Dimensions are (z,y,x) as defined in Ghahramani et al. (2025), with z being range from the transducer surface (horizontal in room coordinates), y the azimuthal array direction (horizontal in room coordinates), and x the elevational array direction (vertical in room coordinates). The RFA probe was placed with its tip approximately at the center of this volume, with its needle parallel to the x axis.
IQ_echo_data:
60x60x60x2xN complex array containing beamformed, demodulated IQ (in-phase/quadrature) echo data interpolated onto the same grid. The array of echo volumes comprises N pairs (one pair acquired every 22 s), with the two volumes from each pair separated by the inter-frame time of 50 ms.
instantaneous_decorrelation:
60x60x60xN real array containing echo decorrelation per ms (linear scale) computed for each frame pair, using the equation and methods from section 2.3 in Ghahramani et al. (2025).
thermocouple_locations:
4x3 real array (same for each trial), with each row comprising the (z,y,x) coordinates (voxel indices within the 60x60x60 grid) of a corresponding thermocouple integrated into the RFA probe.
thermocouple_temperatures:
4xM real array, with each row comprising the measured temperatures (degrees C) measured during ablation, synchronous with the last M ultrasound IQ and decorrelation frames of each trial (not available for trials 30, 78, 91, and 102-109).
decorrelation_at_thermocouples:
4xM real array, with each row comprising the measured decorrelation per ms (linear scale) at each thermocouple location, synchronous with the last M ultrasound IQ and decorrelation frames of each trial.