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  • Advancements in automated nuclei segmentation for histopathology using you only look once-driven approaches

    Type:
    Article
    Description/Abstract:
    Histopathology image analysis plays a pivotal role in disease diagnosis and treatment planning, relying heavily on accurate nuclei segmentation for extracting vital cellular information. In recent years, artificial intelligence (AI) and in particular deep learning models have been applied successfully in solving computational pathology image analysis tasks. The You Only Look Once (YOLO) object detection framework, which is based on a convolutional neural network (CNN) architecture has gained traction across various domains for its real-time processing capabilities. This systematic review aims to comprehensively explore and evaluate the advancements, challenges, and applications of YOLO-based methodologies in nuclei segmentation within the domain of histopathological images. The review encompasses a structured analysis of recent literature, focusing on the utilization of YOLO variants for nuclei segmentation. Key methodologies, training strategies, dataset specifics, and performance metrics are evaluated to elucidate the strengths and limitations of YOLO in this context. Additionally, the review highlights the unique characteristics of YOLO that enable efficient object detection and delineation of nuclei structures, offering a comparative analysis against traditional segmentation approaches. This systematic review underscores the promising outcomes achieved through YOLO-based architectures, emphasizing their potential for accurate and rapid nuclei segmentation. Furthermore, it identifies persistent challenges such as handling variances in nuclei appearances, optimizing model architectures for histopathological images, and improving generalization across diverse datasets. Insights derived from this review can provide a foundation for future research directions and enhancements in nuclei segmentation methodologies using YOLO within histopathology, fostering advancements in disease diagnosis and biomedical research.
    Creator/Author:
    Debsarkar, Shyam
    Submitter:
    Shyam Debsarkar
    Date Uploaded:
    12/28/2025
    Date Modified:
    12/28/2025
    Date Created:
    March 25, 2025
    License:
    All rights reserved

  • Globalization of The Adoration: Pilgrimage, Trade, and Shifting Perspectives within The Master of the Legend of Saint Lucy’s 'Adoration of the Magi' (c. 1480-85)

    Type:
    Document
    Description/Abstract:
    By considering various depictions of the Adoration of the Magi between 1400 to 1485, I establish that the portrayal of the Magus within The Master of the Legend of Saint Lucy’s painting directly reflects the economic realities in Bruges throughout the same period. In turn, my close examination of marketplace standards alongside themes of pilgrimage, shifting racial ideals, and a growing interest in secular subjects, offers new insight into 15th century adaptations of the Adoration.
    Creator/Author:
    Wells, Maiana
    Submitter:
    Maiana Wells
    Date Uploaded:
    04/29/2025
    Date Modified:
    04/29/2025
    Date Created:
    2025-04-30
    License:
    All rights reserved

  • Globalization of The Adoration: DAAPworks Poster 2025

    Type:
    Image
    Description/Abstract:
    Maiana Wells, Department of Art History, University of Cincinnati (DAAPworks).
    Creator/Author:
    Wells, Maiana Lynn
    Submitter:
    Maiana Wells
    Date Uploaded:
    04/28/2025
    Date Modified:
    04/28/2025
    Date Created:
    2025-04-27
    License:
    All rights reserved

  • Monarch butterflies (Danaus plexippus) only use magnetic cues for migratory directionality with orientation re-calibrated by coldness - data file

    Type:
    Dataset
    Description/Abstract:
    Data of monarchs subjected to righting response orientation trials under different artificial magnetic fields pre- and post-overwintering cold treatment.
    Creator/Author:
    Shively-Moore, Samuel
    Submitter:
    Samuel Shively-Moore
    Date Uploaded:
    03/25/2025
    Date Modified:
    05/21/2025
    License:
    Attribution-NonCommercial 4.0 International

  • Lingual-Swallowing Functions Raw Data

    Type:
    Dataset
    Description/Abstract:
    Data collected for a project under the Dysphagia Rehabilitation Lab at the University of Cincinnati. The manuscript was submitted to the American Journal of Speech Language Pathology and is currently under review. Below is the abstract. Purpose: Manometric measures of lingual function are widely used in clinical practice, premised on the assumption that lingual impairments affect oropharyngeal swallowing. This study assessed correlations between measures of lingual function and oropharyngeal swallowing impairments using the Modified Barium Swallow Impairment Profile (MBSImP). Method: Participants undergoing routine Modified Barium Swallow Studies (MBSS) were recruited if able and willing to complete the lingual measurement protocol. Post-MBSS, participants completed the Eating Assessment Tool (EAT-10) and measures of lingual pressure during a saliva swallow, anterior maximum isometric press (aMIP), effortful swallow, anterior isometric endurance (ISO-M), and anterior isotonic endurance (ISO-T). Correlations between these measures and MBSImP Oral Total (OT) and Pharyngeal Total (PT) Overall Impression scores and Penetration-Aspiration Scale (PAS) scores were evaluated using Spearman’s correlation coefficients. Results: The final sample included 41 patients (23 men, 18 women; M= 61.75 ± 14.72 years) with heterogenous diagnoses. Analyses showed a moderate, significant negative correlation between aMIP and Oral Total (rs = -0.44, p < .01), and ISO-M and OT (rs = -0.36, p = .02). Specifically, aMIP was strongly correlated with oral residue (Component 5; rs = -0.49, p < .01), and ISO-M with tongue control during bolus hold (Component 2; rs = -0.47, p < .01). No significant correlations were found with Pharyngeal Total, EAT-10 or PAS scores. Conclusions: Some lingual measurements correlate with oral physiological impairments, suggesting potential utility as clinical indicators of oral swallowing physiology. Further research is needed to explore these relationships across different patient populations.
    Creator/Author:
    Mira, Amna
    Submitter:
    Amna Mira
    Date Uploaded:
    02/05/2025
    Date Modified:
    02/05/2025
    License:
    Open Data Commons Public Domain Dedication and License (PDDL)

  • Vascular motion in the dorsal root ganglion sensed by Piezo2 in sensory neurons triggers episodic neuropathic pain

    Type:
    Dataset
    Description/Abstract:
    The dataset includes all the data used to generate figures for the article submitted to the journal of Neuron. This includes individual figure panels and the raw data used to generate each figure panel, as well as the statistical analyses for each experiment.
    Creator/Author:
    Zhang, Jun-Ming
    Submitter:
    Jun-Ming Zhang
    Date Uploaded:
    01/28/2025
    Date Modified:
    02/26/2025
    Date Created:
    2022-2025
    License:
    All rights reserved

  • methane emissions from natural gas streetlights in Cincinnati, Ohio

    Type:
    Dataset
    Description/Abstract:
    Methane emissions from natural gas streetlights. Measurements were made by Dr. Amy Townsend-Small and her students.
    Creator/Author:
    Townsend-Small, Amy
    Submitter:
    Amy Townsend-Small
    Date Uploaded:
    11/20/2024
    Date Modified:
    11/20/2024
    Date Created:
    2024-11-20
    License:
    Public Domain Mark 1.0

  • locations of natural gas streetlights in Cincinnati

    Type:
    Dataset
    Description/Abstract:
    Locations of natural gas streetlights in Cincinnati, Ohio
    Creator/Author:
    Townsend-Small, Amy
    Submitter:
    Amy Townsend-Small
    Date Uploaded:
    11/20/2024
    Date Modified:
    11/20/2024
    Date Created:
    2024-11-20
    License:
    Public Domain Mark 1.0

  • Slide 086; Bernard Mihalovitch Residence, Photo

    Type:
    Image
    Description/Abstract:
    Slide presentation given by Walter E. Langsam on Desjardins & Hayward, a firm active in the Cincinnati, Ohio area in the late 19th century and early 20th century.
    Creator/Author:
    Langsam, Walter
    Submitter:
    Cade Stevens
    Date Uploaded:
    10/30/2024
    Date Modified:
    10/30/2024
    License:
    Public Domain Mark 1.0

  • Slide 022: House at 1501 E Mcmillan

    Type:
    Image
    Description/Abstract:
    Slide presentation given by Walter E. Langsam on Desjardins & Hayward, a firm active in the Cincinnati, Ohio area in the late 19th century and early 20th century. Desjardins, S. (Samuel) E. ("Dizzy") (Forestville, Mich., 1856-1916) Highly individual, even eccentric architect; conceivably trained at the Ecole des Beaux-Arts (but not listed by Chafee) or possibly in an atelier as a Frenchman. Practiced on own 1882-1892, 1905, and 1910; with A.W. Hayward, 1893-1903 and 1913-1916; with John G. Drainie, 1906; with John F. Sheblessy, 1907-1909; with Rowland G. Bevis, 1911-1912. Desjardins, buttressed by his various partners and staff, was one of the most creative of Cincinnati’s architects for 30 years, with a fanciful flair in massing, outline, and decoration, often combining elements from different historic sources in a remarkably free way. It was Desjardins’ Cincinnati City Hall competition project, for instance –rather than the more conventional Richardsonian Romanesque design of the winning competitor, Samuel Hannaford & Sons– that was published in the influential American Architect & Building News (9/10/1887). Among Desjardins' and his firm's most important works are the 7th Presbyterian Church at 1721 Madison Rd., SEC Cleinview Ave., E. Walnut Hills, which burnt several years ago (the striking tower remains above the modern sanctuary); as well as churches of the Christian denomination in Paris, Winchester, and Cynthiana, Ky. A 1904 account mentions a distillery in Old Mexico, a summer cottage in Nova Scotia, and a church in Alaska. The Greek Revival Bell House in Bell Court in Lexington, Ky., was lavishly remodeled by Desjardins after a fire in the 1880s, and is now open to the public. It was suburban residences, however, that probably gave Desjardins' picturesque talent the freest rein. A most valuable source, The Autograph Book of Suburban Houses, prepared by Desjardins & Hayward in 1895, has just been discovered. It appears to consist of about 175 sheets of exquisite India-ink original drawings (hence the name "Autograph Book") of about 75 houses, most in the Cincinnati area (but not including the Ravogli House). For each residence, there is a perspective of the exterior, in great detail and framed by convincing foliage; a number of houses also have first and second floor plans, and a very few also have interior views of the entrance-stair-halls. These designs vary from Richardsonian Romanesque, Chateauesque, "Queen Anne" and Shingle Style, to early Colonial Revival, but usually have quaint features of their own. The interior plans also reveal some fantastic spatial affects, particularly in the treatment of staircases and polygonal rooms. Many of these houses survive, although some are in deteriorated condition in no-longer-fashionable neighborhoods. Desjardins & Hayward exhibited residences in Cincinnati (as part of the AIA Circuit Drawings show) at the 1st exhibit sponsored by the Cincinnati Chapter of the American Institute of Architects held at the Cincinnati Art Museum in 1901; designs for a university and a church at the 2nd CAIA/CA (1902); and a court house, competition design for the Cincinnati Law school, et al., at the 3rd CAIA/CAM (1903). Desjardins & Sheblessy, interestingly, exhibited also at the 1st CAIA/CAM (1901; when J.F. Sheblessy was probably still located in Louisville); and various buildings at the 4th CAIA/CAM (1908). An article on "The Genius of Michael Angelo [sic]" by Desjardins, originally given before the Cincinnati Chapter of the AIA on May 20, 1902, was published in The American Architect, LXXVI, 1382 (June 21, 1902), 91-93. Obituary, Western Architect & Builder, XXIV, 7 (12/1916); Desjardins & Hayward advertisement, "A Tour of Fourth Street, Cincinnati" (ca. 1892); numerous listings for individual buildings in AA&BN, IA, AR, and WA&B; Nuxhall, SGC, 23, Lot 2.
    Creator/Author:
    Langsam, Walter
    Submitter:
    Walter Langsam
    Date Uploaded:
    10/23/2024
    Date Modified:
    10/31/2024
    License:
    Public Domain Mark 1.0