Data collected for a project under the Dysphagia Rehabilitation Lab at the University of Cincinnati. The manuscript was submitted to the American Journal of Speech Language Pathology and is currently under review. Below is the abstract.
Purpose: Manometric measures of lingual function are widely used in clinical practice, premised on the assumption that lingual impairments affect oropharyngeal swallowing. This study assessed correlations between measures of lingual function and oropharyngeal swallowing impairments using the Modified Barium Swallow Impairment Profile (MBSImP).
Method: Participants undergoing routine Modified Barium Swallow Studies (MBSS) were recruited if able and willing to complete the lingual measurement protocol. Post-MBSS, participants completed the Eating Assessment Tool (EAT-10) and measures of lingual pressure during a saliva swallow, anterior maximum isometric press (aMIP), effortful swallow, anterior isometric endurance (ISO-M), and anterior isotonic endurance (ISO-T). Correlations between these measures and MBSImP Oral Total (OT) and Pharyngeal Total (PT) Overall Impression scores and Penetration-Aspiration Scale (PAS) scores were evaluated using Spearman’s correlation coefficients.
Results: The final sample included 41 patients (23 men, 18 women; M= 61.75 ± 14.72 years) with heterogenous diagnoses. Analyses showed a moderate, significant negative correlation between aMIP and Oral Total (rs = -0.44, p < .01), and ISO-M and OT (rs = -0.36, p = .02). Specifically, aMIP was strongly correlated with oral residue (Component 5; rs = -0.49, p < .01), and ISO-M with tongue control during bolus hold (Component 2; rs = -0.47, p < .01). No significant correlations were found with Pharyngeal Total, EAT-10 or PAS scores.
Conclusions: Some lingual measurements correlate with oral physiological impairments, suggesting potential utility as clinical indicators of oral swallowing physiology. Further research is needed to explore these relationships across different patient populations.
The dataset includes all the data used to generate figures for the article submitted to the journal of Neuron. This includes individual figure panels and the raw data used to generate each figure panel, as well as the statistical analyses for each experiment.
ABSTRACT
Purpose: Tongue manometry (i.e. tongue pressure measurement) is a commonly used assessment for patients with suspected oral-motor involvement in swallowing disorders. Availability of lingual manometry has changed in recent years, with the introduction of the TongueometerTM device being a more affordable tongue manometry system. The purpose of this study was to test concurrent (criterion) validity of the TongueometerTM compared to the current standard reference device, the Iowa Oral Performance Instrument, IOPI®.
Method: Adults without dysphagia were recruited for participation in this study. Standard lingual measurements (swallowing-related pressures, maximum isometric pressure (MIP), and maximum isometric endurance) were recorded, with the bulb anteriorly placed, with both devices, in a randomized order. The Bland-Altman method was used to determine concurrent (criterion) validity of these measurements compared to the clinical standard IOPI® device. A recently available suggested corrective value by Curtis and colleagues (2023) was also applied, with comparisons made between devices both with and without the Curtis correction.
Results: The final sample included 70 adult participants aged 20-89 years (average age 52.3 years). Measures with the TongueometerTM device were significantly lower when compared with the same measures taken using the IOPI® (p<0.01) for all measures including MIP, endurance, and swallow pressures. The correction suggested by Curtis and colleagues did not ameliorate these differences.
Conclusions: The TongueometerTM lingual measurements were consistently lower compared to the IOPI®. Clinical use of values taken with the TongueometerTM device should be compared to normative data published for each specific device. Available features of each device (e.g. display, bulb texture, technology/application) should be considered when selecting which device to use with an individual patient.
"Organizational Response to Emerging Threats" is a project that addresses three separate threat areas -- cybersecurity, peacekeeping and energy security. The data collection for cybersecurity and energy security has been completed. As of June 2019, the data collection for peacekeeping is ongoing. The project documents are organized around three topics, reflected in the filenames -- cybersecurity, peacekeeping and energy security.
The overall purpose/rationale of this research project is to develop a framework that explains how different international organizations (IOs) respond to various emerging threats in international relations. These threats can vary and include cybersecurity, energy security, food security, environmental security, and others. For the purpose of our study we focus on two major variables explaining organizational response: (1) IOs’ capacity to acquire and deploy organizational assets (also referred to as asset fungibility), and; (2) IOs’ ability to make swift decisions in response to changing internal and external environments. Drawing from primary sources including interviews with NATO and EU officials, we suggest a new model explaining when organizations are better equipped at addressing cyber threats, when they have capacity to response more effectively, and what they could do to improve their organizational responses in this area.
The QDR repository contains interviews with policy makers and senior bureaucrats conducted in 2016, 2017, 2018 and 2019 in Brussels, Belgium, and the Hague, the Netherlands. These interviews have been conducted in person or over skype. Approval to conduct interviews has been granted by the University of Cincinnati's IRB (Study ID: 2018-3371.
Retrospective chart review project of subjects receiving lumbar epidural steroid injections for low back pain associated with degenerative disc disease. The primary objective was to compare the efficacy of two different steroids used during the time period studied, methylprednisolone and triamcinolone.
This microsatellite dataset was constructed using eight microsatellite loci with 270 individual samples, representing wild population of Euonymus fortunei in Ohio, Kentucky, Kansas, and Minnesota. Also represented are multiple individuals from several Euonymus cultivars and also wild E. alatus (burning bush) from Ohio. This database is published as Elam RJ and Culley TM (2023) Genetic Analysis of Invasive Spread of Euonymus fortunei (Wintercreeper), a Popular Ornamental Groundcover. Invasive Plant Science and Management.