This Poster describes a collaborative research project between the Culley and Tepe labs in the UC Department of Biology and UC Libraries Digital Scholarship Center presented at the 2017 UC Data Day ( https://libapps.libraries.uc.edu/blogs/dataday/past-data-days/). The project explores publication patterns of research involving hotspot areas of biodiversity and if researchers from developing countries which tend to have most of the biodiversity hotspots, are adequately represented as authors in the scientific literature indexed in Scopus (TM-Elsevier), JSTOR, and PubMed.
The Retrosplenial Cortex (RSC) has a persistent role in the establishment of spatial and contextual memory, with also the connections between visuo-spatial association cortices. The RSC’s ability to form afferent and efferent connections with the Parahippocampal areas of the brain allow it to be another prime location in the brains of both rodents and humans where multiple cues are linked together in memory formation, storage and retrieval of Long Term Memories. Due to the high nature of memory formation and retrieval, the RSC has become a section of the brain that in recent years has been more heavily focused on for the research of Alzheimer’s and Dementia. The RSC has not been examined fully in previous studies with examination of the expression of the apolipoprotein E (APOE) gene along with other genetic and regulatory factors. There are 3 major alleles of the APOE gene (APOE2, APOE3, and APOE4), with APOE4 having the greatest risk for AD. In this research, I identify the relative connection between DEK the proto-oncogene and APOE3 and APOE4 in a rodent model, looking specifically at the RSC and how it affects spatial memory with an induced model of chronic stress.