Index Catalog // Scholar@UC

MSRI research initiative

Type:: Student Work
Description/Abstract:: Creating a database for medical research
Creator/Author:: Macdonald, Melissa
Submitter:: Melissa Macdonald
Date Uploaded:: 10/04/2016
Date Modified:: 10/04/2016
License:: All rights reserved

Genomic transcription of b-catenin MSRI

Type:: Student Work
Description/Abstract:: How wnt affects gut tube patterning
Creator/Author:: Macdonald, Melissa
Submitter:: Melissa Macdonald
Date Uploaded:: 10/04/2016
Date Modified:: 10/04/2016
License:: All rights reserved

Genomic transcription of smad1 MSRI

Type:: Student Work
Description/Abstract:: How bmp regulates formation of gut tube
Creator/Author:: Macdonald, Melissa
Submitter:: Melissa Macdonald
Date Uploaded:: 10/04/2016
Date Modified:: 10/04/2016
License:: All rights reserved

Analyzing metal residues in high speed ball mill synthesis using ICP-MS

Type:: Student Work
Description/Abstract:: Ball milling is used in industry to grind ores, minerals, ceramics, and recently has been implemented to research synthesis of organic compounds. One project is researching nickel catalysis in high speed ball milling for producing substituted cyclooctatetraene compounds. In the process of synthesizing the compounds, Ni, Cr, and Fe residues from the vials and nickel pellets used for the reaction will remain in the product. To analyze for the metals remaining in the product, Inductively Coupled Plasma paired with Mass Spectrometry was used. Initially used as an internal standard, gallium’s mass was found on the spectrometer. It is suspected to be a false positive caused by a FeO+ or FeN+. The product was analyzed using Agilent Technologies 7700 ICP-MS before and after a filtering process. This helped determine how effective the filtering process was removing metals and what concentration remained at the part per billion level (ppb) in the final product. A calibration curve was made with a blank, 1ppb, 5ppb, 10ppb, 25ppb, and 50ppb with Sc as the internal standard. Results showed that chromium is insignificant (<0.0ppb), and iron is approximately 1ppb in concentration. Before the filtration process, nickel is approximately 10ppb, after filtration, nickel’s concentration is insignificant (<0.0ppb).
Creator/Author:: Burgstrom, Eric
Submitter:: eric burgstrom
Date Uploaded:: 04/18/2017
Date Modified:: 04/18/2017
License:: All rights reserved

Using Eye Tracking to Assess the Appeal of Specific Colors

Type:: Student Work
Description/Abstract:: This project aimed at effectively implementing eye tracking MATLAB. The team created an eye tracking program that uses a webcam to locate where a person is looking on a computer screen. The program was tested with a simple experiment that presented the user with a set of colors and found which colors the user looked at most.
Creator/Author:: Jones, Benjamin; Kidd, DeAnna; Clark, Hannah, and Smiley, Caleb
Submitter:: Caleb Smiley
Date Uploaded:: 04/26/2017
Date Modified:: 04/26/2017
License:: All rights reserved

The Importance of Order of Draw in Phlebotomy and the Reduction of Error in the Clinical Laboratory

Type:: Student Work
Description/Abstract:: Improper phlebotomy practice is among one of the most important, and more so, overlooked issues in laboratory medicine. Lab practices involving phlebotomy are critical for diagnostic purposes as erroneous results from incorrect collection can result in potentially life threatening misdiagnoses or treatment routes. This pre-analytical error can result in misleading hyperkalemia and hypocalcemia illustrated in otherwise healthy patients. Improper order of draw can incur costs for both the patient and healthcare facility. Preventative measures must be employed to reduce such adverse events from reoccurring as this singular error can lead to a domino effect of continuous error if not recognized and investigated.
Creator/Author:: Lescano, Victor; Brickler, Jeremiah, and Jackson, Nikala
Submitter:: Nikala Jackson
Date Uploaded:: 04/27/2017
Date Modified:: 04/27/2017
License:: All rights reserved

Characterization of Polymers using High Performance Liquid Chromatography

Type:: Student Work
Description/Abstract:: The purpose of this project was to develop a method to characterize polymers using size exclusion chromatography. Specifically, high performance liquid chromatography coupled with a refractive index detector (RID) was used. Polyethylene glycol (PEG) was used a standard for this method. The mobile phase used was dimethylformamide (DMF). Three different mixtures of PEG polymers with known molecular weights were analyzed to characterize the molecular weight of polyacrylic acid (PAA). After running all polymers, retention times were taken and plotted on the x-axis along with LogMp (molecular weight) on the y-axis. A calibration curve was created and plugged in the retention time of PAA to the line equation. We then, took 10 to the power of that number and calculated a molecular weight of 52292.97 g/mol. This method was shown to be an effective way to characterize polymers using PEG as a standard. Poly (methyl methacrylate), otherwise known as P(MMA), was also tested using the same method. The known weight of the polymer was 60,500 g/mol. After running the polymer, 23,000 g/mol was calculated to be the molecular weight. This molecular weight shows that certain parameters like polarity needs to be considered when running samples on the HPLC.
Creator/Author:: Scowden, Mitchell; Ho, Anh, and Midinov, Beksultan
Submitter:: Mitchell Scowden
Date Uploaded:: 05/09/2018
Date Modified:: 05/09/2018
Date Created:
License:: All rights reserved

MFA Show 2015 — Projects and Texts by MFA students with Art Education and Art History graduate students

Type:: Student Work
Description/Abstract:: UC SCHOOL OF ART MFA GRADUATING SHOW 2015 — TEXTS AND PROJECTS This collection of texts and images brings together the work of graduate students and faculty in art history, art education, and fine arts at the University of Cincinnati in the spring of 2015. We invited students in art education and art history to write accompanying texts for the final projects of their peers in the fine arts graduate program – projects encompassing everything from multimedia installation, abstract painting, video animation, fiber-based sculptural assemblages, photography, and drawing. The students’ projects were presented at the Contemporary Arts Center, Cincinnati, as part of the School of Art’s MFA Thesis Exhibition, which ran from April 1 and April 25, 2015. A process of looking, talking, looking again, writing, reading, and re-writing unfolded. Shorter versions of the texts were shown at the CAC alongside the artworks at the CAC. The process created a working space for artists and writers in dialogue, giving rise to new ideas and projects in turn. Morgan Thomas Vittoria Daiello [from Foreword] Design: Sso-Rha Kang
Creator/Author:: Stenger, Kate; Spires, Lauren; Thomas, Morgan; Daiello, Vittoria; Norton, Ben; Kang, Sso-Rha; Lang, Gabrielle; Johnson, Leigh; Wyatt Bauman, Emily; Karimi, Saeide; Tinney, Ross; Turner, Miles; Oswald, Sean; Klimesh, Colin; Asadipour, Saeedeh; Girandola, Joe; Morren, Samuel; Drout, Julie; Wolhoy, Rick, and Horwitz, Ian
Submitter:: Morgan Thomas
Date Uploaded:: 09/20/2018
Date Modified:: 05/23/2019
Date Created:: 2015-04-27
License:: All rights reserved

Maple Knoll mobile medication cart

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Almofadda, Abdulrahman and Albader, Marwan
Submitter:: CEAS Library Staff
Date Uploaded:: 05/17/2017
Date Modified:: 05/17/2017
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Electronic Classroom Support Services Digital Dashboard

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Edmondson, Phillip P.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2001-06-01
License:: Attribution-NonCommercial-NoDerivs 4.0 International

2019 University of Cincinnati SAE Baja body & safety

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Brown, Shawn
Submitter:: CEAS Library Staff
Date Uploaded:: 05/07/2019
Date Modified:: 05/07/2019
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Cardinal Banc Web Site

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Wheatley, Kelton and Monroe, Jeremy
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2005-03-10
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Voters United for Equality Database and Web Site

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Flick, Anthony R.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2001-05-22
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Work Order Request Form (WORF)

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Baker, Edward J.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2003-06-05
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Transparent Wireless Authentication

Type:: Student Work
Description/Abstract:: A Proposal Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Krebs, Timothy G.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2005-03-06
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Automated powder coat machine

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Arand, Andrew R.
Submitter:: CEAS Library Staff
Date Uploaded:: 05/04/2017
Date Modified:: 05/04/2017
License:: Attribution-NonCommercial-NoDerivs 4.0 International

2017 Bearcats Baja SAE - Steering system

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Wessels, Eric
Submitter:: CEAS Library Staff
Date Uploaded:: 05/09/2017
Date Modified:: 05/09/2017
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Directory Web Site Management System

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Zielinski, Jon
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2005-05-31
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Compact Framework Directional Interface

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Technology
Creator/Author:: Young, Matt
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2006-05-30
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Development of a Wireless Network and Report Building Program for Children's Hospital

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Vernon, Nicholas A.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2002-03-13
License:: Attribution-NonCommercial-NoDerivs 4.0 International

2018 University of Cincinnati SAE baja

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Gardner, Vincent
Submitter:: CEAS Library Staff
Date Uploaded:: 05/09/2018
Date Modified:: 05/09/2018
Date Created:
License:: Attribution-NonCommercial-NoDerivs 4.0 International

An All Linux Network with Integrated Monitoring Systems

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Schutte, Jay and Vinson, Elton
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2005-03-07
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Hybrid jet drive boat

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Finkenkeller, Andrew and Zakrzewski, Cameron
Submitter:: CEAS Library Staff
Date Uploaded:: 05/23/2019
Date Modified:: 05/23/2019
License:: Attribution-NonCommercial-NoDerivs 4.0 International

ZSTEST

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Storer, Zachary J.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2001-05-30
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Equipment and Help Calls Management System

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Hsu, Kevin
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2003-06-11
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Conference Registration Management Application: CRMA

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Duwel, Christopher A.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2004-06-03
License:: Attribution-NonCommercial-NoDerivs 4.0 International

The Reading Online Learning & Collaboration Portal

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Bland, Justin J. and Waters, Lisa Beth
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2006-03-03
License:: Attribution-NonCommercial-NoDerivs 4.0 International

I Tutor: Math for 4th, 5th, and 6th Grade

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Bui, Kinh
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2006-03-06
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Felix: a better embedded systems development kit

Type:: Student Work
Description/Abstract:: senior design capstone report
Creator/Author:: Norton, Ryan Michael
Submitter:: CEAS Library Staff
Date Uploaded:: 05/06/2019
Date Modified:: 05/06/2019
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Implementing an Active Directory Network

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Shumaker, Clint and Powers, Scott
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2006-06-08
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Painter’s DataBase version 1

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in partial fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Moore, Nathan
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2001-05-31
License:: Attribution-NonCommercial-NoDerivs 4.0 International

2018 Unversity of Cincinnati SAE baja frame

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Mulholand, Connor
Submitter:: CEAS Library Staff
Date Uploaded:: 05/09/2018
Date Modified:: 05/09/2018
Date Created:
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Online Bookstore

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Shah, Priya
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2000-03-14
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Interactive penguin fish dispenser

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Diaz, Kristen and Patterson, Nathan
Submitter:: CEAS Library Staff
Date Uploaded:: 05/28/2019
Date Modified:: 05/28/2019
License:: Attribution-NonCommercial-NoDerivs 4.0 International

PC Cash – a Cash Settlement System

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Evers, Jeffrey S.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2002-05-20
License:: Attribution-NonCommercial-NoDerivs 4.0 International

DB Analyzer

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Wortham, Nikkolus
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2004-03-08
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Smart walker

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Brown, Kristen and Oty, Leah
Submitter:: CEAS Library Staff
Date Uploaded:: 05/08/2017
Date Modified:: 11/01/2018
Date Created:
License:: Attribution-NonCommercial-NoDerivs 4.0 International

MLRS TCS Electronic Function Tester

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Mattison, Larry
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2004-06-03
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Hixson's Quality Assurance Application

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Lucchetta, John J.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2006-03-10
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Web Based Program to Improve our Clients Ordering System

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Horvath, Steve Jr.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2001-03-12
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Road trike: suspension and drivetrain

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Bloom, Devon
Submitter:: CEAS Library Staff
Date Uploaded:: 05/07/2019
Date Modified:: 05/07/2019
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Client Management Software

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Cheers, Felicia
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2005-06-03
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Super 8 mm film digitizer

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Stewart, Christopher
Submitter:: CEAS Library Staff
Date Uploaded:: 05/09/2018
Date Modified:: 05/09/2018
Date Created:
License:: Attribution-NonCommercial-NoDerivs 4.0 International

On Target – An Enterprise Application for Target Marketing

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Wethington, Michael Kevin
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2001-05-29
License:: Attribution-NonCommercial-NoDerivs 4.0 International

ADVANCE Informal Website

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Bloodworth, Michael
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/10/2017
Date Created:: 2008-06-08
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Web-Based Inventory Database Application

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Seigla, Garald Emerson
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2002-05-21
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Vietnamese Language CD

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Nguyen, Nguyen and Tran, Ngoc
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2005-03-03
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Electronic Testing and Evaluation System: eTES

Type:: Student Work
Description/Abstract:: Submitted to the Faculty of the Information Engineering Technology Program in Partial Fulfillment of the Requirements for the Degree of Bachelor of Science in Information Engineering Technology
Creator/Author:: Sibley, Wayne A.
Submitter:: CECH Library Service
Date Uploaded:: 03/09/2017
Date Modified:: 03/09/2017
Date Created:: 2004-03-16
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Coupler concept

Type:: Student Work
Description/Abstract:: Senior design capstone report
Creator/Author:: Kropczynski, Peter
Submitter:: CEAS Library Staff
Date Uploaded:: 05/09/2017
Date Modified:: 05/09/2017
License:: Attribution-NonCommercial-NoDerivs 4.0 International

Golgi Tendon Organ Development and Contracture Formation Following Neonatal Brachial Plexus Injury

Type:: Student Work
Description/Abstract:: Neonatal Brachial Plexus Injury (NBPI) is a common birth injury to the nerves innervating the upper limb. A poorly understood and currently incurable consequence of this injury is tightness of affected muscles, or muscle contractures. Paradoxically, contractures do not occur in a rare form of NBPI (preganglionic) in which afferent (sensory) innervation of the muscle is preserved, in contrast to the more common postganglionic NBPI which causes complete denervation, suggesting a possible role of afferent denervation in contracture formation. Afferent neurons interface with muscle at the spindle and golgi tendon organ (GTO). Previous studies have implicated muscle spindles in contracture formation, but the GTO has not been investigated. Unilateral pre and post-ganglionic NBPIs were created in neonatal mice. Bilateral biceps muscles were harvested four weeks later, cleared, and immunohistochemically stained in whole mounts to assess GTO morphology. The nerves innervating the biceps were sectioned and stained to quantify afferent denervation. Complete denervation by postganglionic NBPI led to loss of GTO in denervated muscles, whereas preservation of afferent innervation in preganglionic NBPI preserved normal GTO morphology. These findings suggest that afferent innervation is required for postnatal GTO maintenance, and that loss of the GTO may play a role in contracture formation.
Creator/Author:: Cornwall, Roger; Nikolaou, Sia; Hu, Liangjun, and Lilly, Tanner
Submitter:: Tanner Lilly
Date Uploaded:: 05/17/2017
Date Modified:: 05/17/2017

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