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  • The slippery wall of scaling electrochemical conversions from the lab to industry

    Media thumbnail: The slippery wall of scaling electrochemical conversions from the lab to industry
    Type:
    Media
    Description/Abstract:
    Maggie Flanders, a rising junior at Case Western Reserve University in Cleveland, Ohio, likens the challenge of scaling electrochemical conversions from the lab to industry to an experience at the indoor climbing gym.
    Creator/Author:
    Flanders, Margaret; Wu, Jingjie, and Payton, Eric J.
    Submitter:
    Eric Payton
    Date Uploaded:
    10/26/2026
    Date Modified:
    10/26/2026
    Date Created:
    2024-07-29
    License:
    Attribution 4.0 International

  • Failure and Mental Health in Research

    Media thumbnail: Failure and Mental Health in Research
    Type:
    Media
    Description/Abstract:
    What does failure and mental health look like in the research space? In this episode, Zachary Hite, A senior Mathematics and Engineering Mechanics major at Lindsey Wilson University, shares his experiences with failure and mental health during a summer research internship, and how it changed his outlook on the true meaning of failure.
    Creator/Author:
    Hite, Zachary; Giovannelli, Tommaso, and Payton, Eric J.
    Submitter:
    Eric Payton
    Date Uploaded:
    10/26/2026
    Date Modified:
    10/26/2026
    Date Created:
    2026-10-26
    License:
    Attribution 4.0 International

  • Research and Time are Like Oil and Water: Hard to Mix and Hard to Separate

    Media thumbnail: Research and Time are Like Oil and Water: Hard to Mix and Hard to Separate
    Type:
    Media
    Description/Abstract:
    Ten weeks spent designing 3D-printable filters that separate oil from water using geometry and machine learning, no chemicals, no machinery. This isn't a highlight reel. It's the real story of a project still in progress: failed simulations, a constant back-and-forth with a graduate student to run analyses for me, and long nights when everyone else was asleep. Jenna Tran, a junior at California Polytechnic State University Pomona, describes what research looks like while it's happening.
    Creator/Author:
    Tran, Jenna L. ; Dursun, Elif B.; Jin, Hanxun, and Payton, Eric J.
    Submitter:
    Eric Payton
    Date Uploaded:
    10/26/2026
    Date Modified:
    10/26/2026
    Date Created:
    2026-07-22
    License:
    Attribution 4.0 International

  • A Sandwich Under The Microscope

    Media thumbnail: A Sandwich Under The Microscope
    Type:
    Media
    Description/Abstract:
    Gabe Carson, a 3rd year materials science major at University of Florida, describes his experience working with thermoelectric devices, where a snapped lab saw upends the plan and forces a crash course in the fiddly, microscope-bound art of sample prep.
    Creator/Author:
    Carson, Gabriel; Watzman, Sarah J., and Payton, Eric J.
    Submitter:
    Eric Payton
    Date Uploaded:
    10/26/2026
    Date Modified:
    10/27/2026
    Date Created:
    2024-07-31
    License:
    Attribution 4.0 International

  • How does slowly stretching metal relate to energy efficiency?

    Media thumbnail: How does slowly stretching metal relate to energy efficiency?
    Type:
    Media
    Description/Abstract:
    Will Hammer, a first-year Mechanical Engineering student at University of Cincinnati describes the slow processes of research and creep deformation in metals.
    Creator/Author:
    Hammer, Will; Erdeniz, Dinc , and Payton, Eric J.
    Submitter:
    Eric Payton
    Date Uploaded:
    10/25/2026
    Date Modified:
    10/27/2026
    Date Created:
    2026-10-25
    License:
    Attribution-NonCommercial 4.0 International

  • Frozen Acoustic and Temporal Models for Analysis of Shelter Dog Vocalizations: Reproducibility Archive

    Dataset thumbnail: Frozen Acoustic and Temporal Models for Analysis of Shelter Dog Vocalizations: Reproducibility Archive
    Type:
    Dataset
    Description/Abstract:
    This archive contains the frozen acoustic and temporal models used to analyze vocalizations recorded in a study examining the effects of partial privacy panels on dog behavior in a shelter dog adoption building. The acoustic detector identifies vocalization events, while the temporal model groups successive events into episodes using a previously established, frozen inter-event interval boundary. The reproducibility package includes Python implementations, model parameters, specifications, event-level and recording-level outputs, verification results, and supporting documentation. The temporal Python implementation was reconstructed from the frozen model specification and verified against archived results; the original three-component mixture model was not refitted. The archive is intended to support transparency, reproducibility, and independent examination of the computational methods used in the study. It does not include the original audio recordings.
    Creator/Author:
    Shyan-Norwalt, Melissa
    Submitter:
    Melissa Shyan-Norwalt
    Date Uploaded:
    10/25/2026
    Date Modified:
    10/25/2026
    Date Created:
    2026-10-03
    License:
    Attribution 4.0 International

  • Acute stress exacerbates spontaneous pain in a sex-dependent manner in mice with nerve injury or bone metastasis

    Dataset thumbnail: Acute stress exacerbates spontaneous pain in a sex-dependent manner in mice with nerve injury or bone metastasis
    Type:
    Dataset
    Description/Abstract:
    Spontaneous pain, characterized by unpredictable, episodic shooting or stabbing sensations, is linked to vasomotion-evoked cluster firing in injured dorsal root ganglion (DRG) sensory neurons. Since acute stress triggers a sympathetic "fight-or-flight" response involving vasoconstriction, we investigated whether stress-induced cardiovascular changes exacerbate neuropathic pain. Spontaneous pain-related behaviors (shaking, flinching, and licking) were recorded in male and female mice with spared nerve injury (SNI). While a 10-min acute restraint stress exposure significantly increased pain scores (flinches/shakes) in male SNI mice, no significant increase was observed in females, who displayed higher baseline spontaneous pain scores. Increased licking was observed in both sexes and in naive mice, suggesting it represents a general stress response rather than pain. Importantly, both the α-adrenoceptor antagonist phentolamine and the β-blocker propranolol prevented stress-induced pain exacerbation. Similar results were observed in a mouse bone cancer pain model, and the vasoconstrictor phenylephrine induced robust c-Fos activation in the ipsilateral spinal dorsal horn in both models. These findings demonstrate that, contrary to typical stress-induced analgesia, acute stress in animals with peripheral neuropathy can exacerbate spontaneous pain through a sex-dependent, sympathetically mediated neurovascular mechanism.
    Creator/Author:
    Jun-Ming Zhang
    Submitter:
    Jun-Ming Zhang
    Date Uploaded:
    10/21/2026
    Date Modified:
    10/21/2026
    Date Created:
    2023-2026
    License:
    All rights reserved

  • Selective Inhibition of A549 Lung Cancer Stem Cell Tumorspheres by a Bacterial Antibiotic Supernatant

    Article thumbnail: Selective Inhibition of A549 Lung Cancer Stem Cell Tumorspheres by a Bacterial Antibiotic Supernatant
    Type:
    Article
    Description/Abstract:
    Authors Patel Y, Maiorano JN, Girard AL, & Shirokawa J. Abstract Non-small cell lung cancer is one of the most prevalent types of cancer that is responsible for the majority of cancer-related deaths worldwide. Recurrence and metastasis continue as a major barriers to the successful treatment of non-small cell lung cancer. Cancer stem cells are a main contributor to cancer recurrence and metastasis thus, a target for lung anticancer therapy. Evidence that some antibiotics are effective cancer stem cell inhibitors makes the identification of new antibiotic cancer stem cell inhibitors a key area in lung anticancer drug discovery. Previously we isolated antibiotic producing bacteria as a part of the Tiny Earth® network and screened their media supernatants for the ability to inhibit cancer stem cells using a tumorsphere assay. One supernatant inhibited breast, prostate, and lung cancer stem cells. In the present study, we find that this antibiotic active supernatant selectively inhibits A549 lung cancer stem cells over bulk A549 lung cancer cells.
    Creator/Author:
    Shirokawa, Jill M.
    Submitter:
    Jill Shirokawa
    Date Uploaded:
    10/01/2026
    Date Modified:
    10/11/2026
    Date Created:
    2025-09-24
    License:
    Attribution 4.0 International

  • Alternate version of Jett Barham's "The Silent Technology Securing American Electrification"

    Media thumbnail: Alternate version of Jett Barham's "The Silent Technology Securing American Electrification"
    Type:
    Media
    Description/Abstract:
    Can magnets repel hurricanes? Well, no... but maybe new magnet technology could play a role in helping prevent future hurricanes. Jett Barham, a 4th year materials engineering undergraduate at the University of Kentucky explores motivations behind research into rare-earth free magnets while sharing his experience as a part of the 2026 REALIZE program at UC.
    Creator/Author:
    Barham, Jett; Mayer, Corrie M.; Steiner, Matthew A., and Payton, Eric J.
    Submitter:
    Eric Payton
    Date Uploaded:
    08/15/2026
    Date Modified:
    08/15/2026
    Date Created:
    2026-07-21
    License:
    Attribution-NonCommercial 4.0 International

  • The Silent Technology Securing American Electrification

    Media thumbnail: The Silent Technology Securing American Electrification
    Type:
    Media
    Description/Abstract:
    Rare earth elements. They are a hot topic in the news... but why? What technologies are they used in? Jett Barham, a materials engineering major at University of Kentucky, describes his summer doing research at University of Cincinnati and how new magnet research could shape the global energy landscape.
    Creator/Author:
    Barham, Jett; Steiner, Matthew A., and Payton, Eric J.
    Submitter:
    Eric Payton
    Date Uploaded:
    08/13/2026
    Date Modified:
    10/27/2026
    Date Created:
    2026-08-13
    License:
    Attribution 4.0 International