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  • Bayesian Approach to Selecting Hyperelastic Constitutive Models of Soft Tissue

    Article thumbnail: Bayesian Approach to Selecting Hyperelastic Constitutive Models of Soft Tissue
    Type:
    Article
    Description/Abstract:
    Hyperelastic constitutive models of soft tissue mechanical behavior are extensively used in applications like computer-aided surgery, injury modeling, etc. While numerous constitutive models have been proposed in the literature, an objective method is needed to select a parsimonious model that represents the experimental data well and has good predictive capability. This is an important problem given the large variability in the data inherent to soft tissue mechanical testing. In this work, we discuss a Bayesian approach to this problem based on Bayes factors. We propose a holistic framework for model selection, wherein we consider four different factors to reliably choose a parsimonious model from the candidate set of models. These are the qualitative fit of the model to the experimental data, evidence values, maximum likelihood values, and the landscape of the likelihood function. We consider three hyperelastic constitutive models that are widely used in soft tissue mechanics: Mooney-Rivlin, Ogden and exponential. Three sets of mechanical testing data from the literature for agarose hydrogel, bovine liver tissue, porcine brain tissue are used to calculate the model selection statistics. A nested sampling approach is used to evaluate the evidence integrals. In our results, we highlight the robustness of the proposed Bayesian approach to model selection compared to the likelihood ratio, and discuss the use of the four factors to draw a complete picture of the model selection problem.
    Creator/Author:
    Madireddy, Sandeep; Vemaganti, Kumar, and Sista, Bhargava
    Submitter:
    Kumar Vemaganti
    Date Uploaded:
    01/21/2015
    Date Modified:
    05/23/2019
    Date Created:
    2015-01-21
    License:
    All rights reserved

  • A computational study of the dynamic propagation of two offset cracks using the phase field method

    Article thumbnail: A computational study of the dynamic propagation of two offset cracks using the phase field method
    Type:
    Article
    Description/Abstract:
    The study of the propagation of multiple cracks is essential to modeling and predicting structural integrity. The interaction between two cracks depends on a number of factors such as the domain geometry, the relative crack sizes and the separation between the two crack tips. In this paper, we study the interaction between two dynamically propagating cracks. We use the phase field method to track the crack paths, since this method can handle complex crack behavior such as crack branching, without any ad hoc criteria for crack evolution. The results from our dynamic simulations indicate that, unlike crack inter- action under quasi-static or fatigue loading, the presence of another crack does not accelerate crack propagation when dynamic loads are applied. However, some similarities in the crack topologies are observed for both quasi-static and dynamic loading.
    Creator/Author:
    Kumar Vemaganti and Sai Deogekar
    Submitter:
    Kumar Vemaganti
    Date Uploaded:
    10/11/2017
    Date Modified:
    10/11/2017
    License:
    All rights reserved