Intelligent Application if defined technically is a strategy that uses hyper-personalized mobile app experiences and services and knowledge-extraction processes to increases the user experience (Jessica Ekholm, 2017). In simple words, the applications that not only know how to support or enable key decisions but also continually learn from the user interactions to become even more relevant and valuable to those users, are known as Intelligent apps. Such applications are smart enough to differentiate between relevant and irrelevant information with the help of AI algorithms. Moreover, these apps have the capability to ease the complex task into the as simple task as a single touch.
This document is a supplement to the University of Cincinnati's Power Session workshop presented at Data Day 2019 by Richard Johansen and Mark Chalmers. The goal of this document is to reproduce the step-by-step instructions of the Power Session which demonstrated how to create interactive maps of social vulnerability at the county level. Familiarity with GitHub, R and RStudio environments are highly recommended, but not required to follow this tutorial. For a more in-depth explanation as to how the data was retrieved, cleaned, and manipulated, please refer to the full R script called Mapping_Social_Vulnerability.R located in the Scripts folder of the GitHub repository.
There was a lack of standardization of care for patients on venoarterial extracorporeal membrane oxygenation (VA ECMO) at Kettering Medical Center. This project discusses the creation and implementation of a standardized VA ECMO physician order set, VA ECMO anticoagulation embedded physician order set, nursing policy and guideline, and standardized electronic health record (EHR) documentation within an ECMO-specific Epic flowsheet.
Programs used and described in the book "Multivariate Public Key Cryptosystems" by Ding, Petzoldt and Schmidt. All programs can be downloaded via the attached zip file. Modify the file "startup.txt" so that the base directory matches your setup. Put this file where magma can find it.
After starting magma run: load "startup.txt"; It will then allow you to select the method on which you want to work.
Files can be downloaded individually by clicking on a chapter name and then selecting the scheme of interest.
In this paper, I study how general technology users perceive the dark web. In this study,
I conducted research on what these users know about dark web technologies, activities,
content, and how their perceptions changed after a first-hand experience on dark web
marketplaces and sites. I aimed to tackle myths and misconceptions that users had about the
dark web and present new data in order to educate and bring awareness to the dark web to
those who may never have the opportunity or reason to come upon this information on their
own. It is my hope that the findings of this paper and the experiences of the participants will
foster the spread of knowledge and awareness to both the threats and benefits that the dark
web contributes to society.
A conversation between two friends who are not musicians and whose personal histories could hardly be more different. Through a series of conversations we explored those journeys, compared and contrasted our stories, and discussed just why this music affects us so deeply. We discussed specific musicians in terms of whether we liked, did not like, or were indifferent to their music, and why we either agreed or not. In these conversations we posed various questions to each other, hoping to discover and articulate certain essences that we might share. One thing we agreed upon up front is that we are neither musicians nor music critics. In fact, we’re not convinced that the field of music criticism is even a valid endeavor. Music description and personal reaction, however, is another matter. In our conversations we tried to describe our reactions to specific musicians and “schools” of music, without labeling the music as “good” or “lousy”. You will see that this doesn’t prevent us from disagreeing and disagreeing in spirited fashion, while always trying to focus on why our personal reaction is what it is.
This document details our process for creating a service catalog for UC Libraries Research and Data Services and our efforts towards offering data science services. In this document, we identify our gaps in knowledge and expertise while making recommendations for filling these gaps.
Cincinnati has one of the lowest home ownership rates in the country for cities of comparable size. Several other cities with low rates of home ownership in 1970 have managed to increase their rates two to four percent over the past 25 years, but the home ownership rate in Cincinnati has been stable over that period at 38 percent.
The best explanation for Cincinnati’s low home ownership rate is that the topography of the city encouraged dense development involving multiple-unit structures up until World War II. When the highway programs of the post-war period opened up the suburbs to development, the city was already built-out and could not compete for new single-unit construction that the federal government was subsidizing on a massive scale.
In the last 50 years, the Hamilton County suburbs have gained 140,000 owners while the number of owners in the city has decreased by 1,000. As a result, the home ownership rate in the Cincinnati metropolitan area is greater than the national rate for areas of comparable size (63 percent versus 61 percent) while the rate in the city is far less than the national rate.
The City of Cincinnati faces a number of challenges in any effort to increase its home ownership rate. Government programs in other cities typically produce dozens of units a year, not the hundreds of units that Cincinnati needs to produce. In order to achieve even a modest increase in home ownership, the city will have to alter market forces in the direction of increased supply of housing suitable for owner-occupancy and increased demand for home ownership.
In order to increase its rate of home ownership to 41 percent by the year 2010, the City of Cincinnati needs to adopt a four-part strategy:
Increase the Supply of Units
The market cannot produce new units on its own. The city needs to assemble and prepare sites in order to reduce the additional costs associated with building in the city as opposed to the suburbs. City Hall must continue to eliminate barriers to development and provide new services to builders. Cincinnati will not be able to increase the number of middle-class owners without creating new neighborhood areas with the appropriate mix of amenities. At the lower end of the owner-market, the city needs to move aggressively to convert abandoned structures into units people will want to buy and rehabilitate.
Help Renters Become Owners
While converting renters to owners is an essential component of an overall strategy, the City of Cincinnati must recognize that not everyone can be an owner and target its resources appropriately. The city does not have unlimited funds to change the cost equation of owning a home and will, therefore, have to learn from other cities how to work with lending institutions to increase the flow of dollars under Community Reinvestment Act initiatives. Other cities have had some limited success with programs to convert people renting duplex and condo units into owners. The city needs to increase the availability, extent and quality of education and counseling programs.
Attract New Households to the City
The city has to market its neighborhoods, and in some cases, smaller areas within neighborhoods. This will require market research, training programs for Realtors, investments in street furniture, increased services, publications extolling city neighborhoods, and programs comparable to the Living in Cleveland program. The city needs to start working cooperatively with the Cincinnati Public Schools. Specific market niches in which the city can hope to compete very successfully include the empty nesters, the gay and lesbian community, first time buyers, and people interested in downtown living.
Maintain the Existing Pool of Owners
About 75 percent of the time a home owner in Cincinnati sells and buys another home in the Cincinnati area, the home purchased will be in the suburbs. The city must create opportunities for the home seller to move up without moving out of the city.
In addition to the above strategies, which involve the central city market, the City of Cincinnati needs to actively promote strategies that will help slow the rate of suburbanization and that will create low income housing opportunities in the suburbs. If suburbanization continues at the current rate, and if the city continues to be the governmental unit with de facto responsibility for low income housing, there is every reason to wonder if there is anything that the city can do to increase its rate of home ownership.
This document is a workshop workbook for EndNote X8, a citation and reference management software product. The workbook provides descriptions and exercises for most of the major features of EndNote, including program customization, importing & exporting data, organization and management of data, full text recovery & management, cite-while-you-write utility and EndNote Online.
Helicobacter pylori (H. pylori) is the major risk factor for the development of gastric cancer. Our laboratory has reported that the Sonic Hedgehog (Shh) signaling pathway is an early response to infection that is fundamental to the initiation of H. pylori-induced gastritis. H. pylori also induces programmed death ligand 1 (PD-L1) expression on gastric epithelial cells, yet the mechanism is unknown. We hypothesize that H. pylori-induced PD-L1 expression within the gastric epithelium is mediated by the Shh signaling pathway during infection. To identify the role of Shh signaling as a mediator of H. pylori-induced PD-L1 expression, human gastric organoids generated from either induced pluripotent stem cells (HGOs) or tissue (huFGOs) were microinjected with bacteria and treated with Hedgehog/Gli inhibitor GANT61. Gastric epithelial monolayers generated from the huFGOs were also infected with H. pylori and treated with GANT61 to study the role of Hedgehog signaling as a mediator of induced PD-1 expression. A patient-derived organoid/autologous immune cell co-culture system infected with H. pylori and treated with PD-1 inhibitor (PD-1Inh) was developed to study the protective mechanism of PD-L1 in response to bacterial infection. H. pylori significantly increased PD-L1 expression in organoid cultures 48 hours post-infection when compared to uninfected controls. The mechanism was cytotoxic associated gene A (CagA) dependent. This response was blocked by pretreatment with GANT61. Anti-PD-L1 treatment of H. pylori infected huFGOs, co-cultured with autologous patient cytotoxic T lymphocytes and dendritic cells, induced organoid death. H. pylori-induced PD-L1 expression is mediated by the Shh signaling pathway within the gastric epithelium. Cells infected with H. pylori that express PD-L1 may be protected from the immune response, creating premalignant lesions progressing to gastric cancer.