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EndNote X8 Workbook
Type: Document Description/Abstract: This document is a workshop workbook for EndNote X8, a citation and reference management software product. The workbook provides descriptions and exercises for most of the major features of EndNote, including program customization, importing & exporting data, organization and management of data, full text recovery & management, cite-while-you-write utility and EndNote Online. Creator/Author: Roberts, Randall Submitter: Randall Roberts Publisher: University of Cincinnati Date Uploaded: 2019-01-23T19:09:20Z Date Modified: 2019-01-23T19:10:28Z Date Created: February 20, 2017 Rights: Attribution-NonCommercial 4.0 International Genre: Document -
Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. Holokai et al., 2018
Type: Dataset Description/Abstract: ABSTRACT Helicobacter pylori (H. pylori) is the major risk factor for the development of gastric cancer. Our laboratory has reported that the Sonic Hedgehog (Shh) signaling pathway is an early response to infection that is fundamental to the initiation of H. pylori-induced gastritis. H. pylori also induces programmed death ligand 1 (PD-L1) expression on gastric epithelial cells, yet the mechanism is unknown. We hypothesize that H. pylori-induced PD-L1 expression within the gastric epithelium is mediated by the Shh signaling pathway during infection. To identify the role of Shh signaling as a mediator of H. pylori-induced PD-L1 expression, human gastric organoids generated from either induced pluripotent stem cells (HGOs) or tissue (huFGOs) were microinjected with bacteria and treated with Hedgehog/Gli inhibitor GANT61. Gastric epithelial monolayers generated from the huFGOs were also infected with H. pylori and treated with GANT61 to study the role of Hedgehog signaling as a mediator of induced PD-1 expression. A patient-derived organoid/autologous immune cell co-culture system infected with H. pylori and treated with PD-1 inhibitor (PD-1Inh) was developed to study the protective mechanism of PD-L1 in response to bacterial infection. H. pylori significantly increased PD-L1 expression in organoid cultures 48 hours post-infection when compared to uninfected controls. The mechanism was cytotoxic associated gene A (CagA) dependent. This response was blocked by pretreatment with GANT61. Anti-PD-L1 treatment of H. pylori infected huFGOs, co-cultured with autologous patient cytotoxic T lymphocytes and dendritic cells, induced organoid death. H. pylori-induced PD-L1 expression is mediated by the Shh signaling pathway within the gastric epithelium. Cells infected with H. pylori that express PD-L1 may be protected from the immune response, creating premalignant lesions progressing to gastric cancer. Creator/Author: Zavros, Yana Submitter: Yana Zavros Publisher: University of Cincinnati Date Uploaded: 2018-12-21T20:49:29Z Date Modified: 2018-12-21T21:10:11Z Rights: All rights reserved -
Transforming the UC Informationist Program: Growing and Aligning Toward Data Science
Type: GenericWork Description/Abstract: The University of Cincinnati (UC) Libraries' Informationist program and Research & Data Services (RDS) unit provide an extensive program of support for the research community. RDS is a highly-integrated unit of UC Libraries, staffed by informationists in the health sciences, sciences, engineering and social sciences and librarians, specialist staff, and student consultants. Our activities infuse across the institution, including the main campus and the Academic Health Center campus, and we oversee innovative spaces that respond to the particular needs of research communities, including informatics, geospatial analysis and data visualization. Since the fall 2015 CNI presentation on the UC Informationists ("New Roles, New Collaborations: Developing an Informationist Program to Support University Research"), we have greatly expanded our partnerships, services and educational offerings. We are now active in data and statistical consulting, collaborations on bioinformatics education, impactful community engagements (e.g., UC Data Day), and deep partnerships with the UC IT unit on initiatives such as the Data & Computational Science Series. At present, we are pursuing a new and challenging vision to realign our work in order to enable the institution's agendas for data science and innovation. We will discuss our experience with scalable growth and other successes in Research & Data Services and our assessment of a future in data science. Creator/Author: Baldwin, Ted and Grant, Tiffany Submitter: Ted Baldwin Publisher: University of Cincinnati Date Uploaded: 2018-12-14T01:25:05Z Date Modified: 2018-12-14T01:27:24Z Date Created: 2018-12-10 Rights: Attribution-NonCommercial-NoDerivs 4.0 International -
American Classical?
Type: Document Description/Abstract: Is jazz serious art music? Is jazz in fact America’s classical music? I contend that much jazz is both. This paper is an exploration of these questions, not a history of jazz, although I will have to recount some historical facts. Rather, it is an examination of this music from two perspectives, seeking a convincing argument for my assertions. Creator/Author: Marine, Stephen Submitter: Stephen Marine Language: English Date Uploaded: 2018-12-07T13:40:54Z Date Modified: 2018-12-07T13:40:54Z Date Created: 2012-11-12 Rights: Attribution-NonCommercial-NoDerivs 4.0 International Time Period: 21st century and 20th century Genre: White Paper -
Publication equality in conservation and plant genetics: The impact of neocolonialism in modern science
Type: Image Description/Abstract: This Poster describes a collaborative research project between the Culley and Tepe labs in the UC Department of Biology and UC Libraries Digital Scholarship Center presented at the 2017 UC Data Day ( https://libapps.libraries.uc.edu/blogs/dataday/past-data-days/). The project explores publication patterns of research involving hotspot areas of biodiversity and if researchers from developing countries which tend to have most of the biodiversity hotspots, are adequately represented as authors in the scientific literature indexed in Scopus (TM-Elsevier), JSTOR, and PubMed. Creator/Author: Barreiro-Sanchez, José; Tunison, Robert; Torres, Maria; Tepe, Eric; Culley, Theresa; Johnson, Arlene; Ammar, Marwa; Elam, Robert; Merritt, Benjamin; Lee, James; Philpott, Megan, and Koshoffer, Amy Submitter: Amy Koshoffer Publisher: University of Cincinnati Language: English, Portuguese, and Spanish Date Uploaded: 2018-10-27T21:06:22Z Date Modified: 2018-11-08T21:58:28Z Date Created: 2017-03 Rights: Attribution-NonCommercial-ShareAlike 4.0 International Time Period: 1970's to 2010's Required Software: pdf reader Genre: Poster -
The Pulse of a Nation: A Study on the Cybersecurity Issues Plaguing the Healthcare Industry
Type: Article Description/Abstract: In this paper, I study how medical records are being used by cyber-criminal for financial gain and patient manipulation. I studied what kind of criminal organizations may be involved in these operations and confirmed incidents from the black market. I conducted a literature review which generated several sources from online databases. I determined five major criminal factions that are most likely to use compromised medical records, determined possible motivations and looked at several cases of medical records being sold on the black market. The healthcare industry’s digitization efforts have left it tremendously ill-equip to combat emerging threats. It is evident that the healthcare industry must take extreme measures in order to counteract the evolving threat landscape. It is my hope that the findings of paper will being to shed light on these issues and help healthcare professionals understand what kind of threats the industry is facing. Creator/Author: Angel, William Submitter: William Angel Publisher: University of Cincinnati Language: English Date Uploaded: 2018-10-10T01:04:25Z Date Modified: 2018-10-10T01:11:06Z Date Created: 2018-04-23 Rights: All rights reserved Time Period: 21st Century -
Zur Geschichte Alexanders des Grossen : page images
Type: Document Description/Abstract: Page scans. For parent work, with complete PDF, see https://scholar.uc.edu/show/hq37vp68b Creator/Author: Petersdorff, Rudolf, 1845- Submitter: Classics Library Staff Date Uploaded: 2018-09-28T18:49:45Z Date Modified: 2018-09-28T18:49:45Z Rights: Public Domain Mark 1.0 -
Zur Geschichte Alexanders des Grossen
Type: Document Description/Abstract: 1-32 p Creator/Author: Petersdorff, Rudolf, 1845- Submitter: Classics Library Staff Publisher: Flensburg, Gedruckt in der Buchdruckerei von L.P.H. Maass, 1872 Language: German Date Uploaded: 2018-09-28T18:47:11Z Date Modified: 2018-09-28T18:47:11Z Date Created: 1872 Rights: Public Domain Mark 1.0 Note: Location: CLASS Stacks Call Number: Diss 7693 OCLC Number: 9882959 On reel 181 beginning frame no. 352 Pages extracted from a Jahresbericht of the Königliches Gymnasium und realschule in Flensburg 1872 Microfilm (negative). Cincinnati, Ohio: Assured Micro-Services, 1983. 1 reel; 16 mm. (University of Cincinnati dissertations, Programmschriften, and pamphlets in classical studies. no. 7693) Königliches Gymnasium und Realschule I. Ordnung zu Flensburg. 1872. Jahresbericht womit zu der Feier des Kaiserlichen Geburtstages am 22ten Mӓrz und zu dem am 21. Mӓrz stattfindenden Redeactus und der Entlassung der Abiturienten ergebenst einladet Dr. Otto Siefert, Director. Vorangeschicht ist: Beitrӓge zur Geschichte des Grossen. Von Dr. Rudolph Petersdorff. Flensburg, Gedruckt in der Buchdruckerei von L.P.H. Maass A study of the history of Alexander the Great (pp. 1-32), along with the Gymnasium’s 1872 annual report commemorating the Kaiser’s birthday and the dismissal of the school graduates. The annual report appears on pp. 33-48. Genre: Pamphlet -
Eine neue Hauptquelle des Q. Curtius Rufus. Beiträge zur Kritik der Quellen für die Geschichte Alexanders des Grossen : page images
Type: Document Description/Abstract: Page scans. For parent work, with complete PDF, see https://scholar.uc.edu/show/7d278v31s Creator/Author: Petersdorff, Rudolf, 1845- Submitter: Classics Library Staff Date Uploaded: 2018-09-28T16:37:11Z Date Modified: 2018-09-28T16:37:11Z Rights: Public Domain Mark 1.0 -
Eine neue Hauptquelle des Q. Curtius Rufus. Beiträge zur Kritik der Quellen für die Geschichte Alexanders des Grossen
Type: Document Description/Abstract: 64 p Creator/Author: Petersdorff, Rudolf, 1845- Submitter: Classics Library Staff Publisher: Hannover, Hahnsche Buchhandlung, 1884 Language: German Date Uploaded: 2018-09-28T16:28:15Z Date Modified: 2018-09-28T16:28:15Z Date Created: 1884 Rights: Public Domain Mark 1.0 Note: Location: CLASS Stacks Call Number: Diss 7692 OCLC Number: 9882942 On reel 181 beginning frame no. 314 Microfilm (negative). Cincinnati, Ohio: Assured Micro-Services, 1983. 1 reel; 16 mm. (University of Cincinnati dissertations, Programmschriften, and pamphlets in classical studies. no. 7692) Digital version at: https://archive.org/details/eineneuehauptqu00petegoog Eine neue Hauptquelle des Q. Curtius Rufus. Beiträge zur Kritik der Quellen für die Geschichte Alexanders des Grossen. Von Dr. R. Petersdorff, Direktor des Gymnasiums zu Strehlen. Hannover, Hahnsche Buchhandlung, 1884 A discussion of a new main source of Q. Curtius Rufus for the examination of the sources for the history of Alexander the Great by Rudolf Petersdorff, director of the Gymnasium at Strehlen. Genre: Pamphlet