Data collected for a project under the Dysphagia Rehabilitation Lab at the University of Cincinnati. The manuscript was submitted to the American Journal of Speech Language Pathology and is currently under review. Below is the abstract.
Purpose: Manometric measures of lingual function are widely used in clinical practice, premised on the assumption that lingual impairments affect oropharyngeal swallowing. This study assessed correlations between measures of lingual function and oropharyngeal swallowing impairments using the Modified Barium Swallow Impairment Profile (MBSImP).
Method: Participants undergoing routine Modified Barium Swallow Studies (MBSS) were recruited if able and willing to complete the lingual measurement protocol. Post-MBSS, participants completed the Eating Assessment Tool (EAT-10) and measures of lingual pressure during a saliva swallow, anterior maximum isometric press (aMIP), effortful swallow, anterior isometric endurance (ISO-M), and anterior isotonic endurance (ISO-T). Correlations between these measures and MBSImP Oral Total (OT) and Pharyngeal Total (PT) Overall Impression scores and Penetration-Aspiration Scale (PAS) scores were evaluated using Spearman’s correlation coefficients.
Results: The final sample included 41 patients (23 men, 18 women; M= 61.75 ± 14.72 years) with heterogenous diagnoses. Analyses showed a moderate, significant negative correlation between aMIP and Oral Total (rs = -0.44, p < .01), and ISO-M and OT (rs = -0.36, p = .02). Specifically, aMIP was strongly correlated with oral residue (Component 5; rs = -0.49, p < .01), and ISO-M with tongue control during bolus hold (Component 2; rs = -0.47, p < .01). No significant correlations were found with Pharyngeal Total, EAT-10 or PAS scores.
Conclusions: Some lingual measurements correlate with oral physiological impairments, suggesting potential utility as clinical indicators of oral swallowing physiology. Further research is needed to explore these relationships across different patient populations.
The dataset includes all the data used to generate figures for the article submitted to the journal of Neuron. This includes individual figure panels and the raw data used to generate each figure panel, as well as the statistical analyses for each experiment.
ABSTRACT
Purpose: Tongue manometry (i.e. tongue pressure measurement) is a commonly used assessment for patients with suspected oral-motor involvement in swallowing disorders. Availability of lingual manometry has changed in recent years, with the introduction of the TongueometerTM device being a more affordable tongue manometry system. The purpose of this study was to test concurrent (criterion) validity of the TongueometerTM compared to the current standard reference device, the Iowa Oral Performance Instrument, IOPI®.
Method: Adults without dysphagia were recruited for participation in this study. Standard lingual measurements (swallowing-related pressures, maximum isometric pressure (MIP), and maximum isometric endurance) were recorded, with the bulb anteriorly placed, with both devices, in a randomized order. The Bland-Altman method was used to determine concurrent (criterion) validity of these measurements compared to the clinical standard IOPI® device. A recently available suggested corrective value by Curtis and colleagues (2023) was also applied, with comparisons made between devices both with and without the Curtis correction.
Results: The final sample included 70 adult participants aged 20-89 years (average age 52.3 years). Measures with the TongueometerTM device were significantly lower when compared with the same measures taken using the IOPI® (p<0.01) for all measures including MIP, endurance, and swallow pressures. The correction suggested by Curtis and colleagues did not ameliorate these differences.
Conclusions: The TongueometerTM lingual measurements were consistently lower compared to the IOPI®. Clinical use of values taken with the TongueometerTM device should be compared to normative data published for each specific device. Available features of each device (e.g. display, bulb texture, technology/application) should be considered when selecting which device to use with an individual patient.
Retrospective chart review project of subjects receiving lumbar epidural steroid injections for low back pain associated with degenerative disc disease. The primary objective was to compare the efficacy of two different steroids used during the time period studied, methylprednisolone and triamcinolone.
Data from qualitative study "Employing Strategies to Address Implicit Racial Bias in the Home Visit Setting" Includes: written reflections by FM residents, resident focus group data, commitments-to-change, and 3-month follow up survey data
This is a preprint of a to be submitted paper that demonstrates that: (1) many important food allergens (eggs, milk, peanuts, tree nuts) induce the unfolded protein response (UPR) in intestinal epithelial cells; (2) induction of the UPR, in turn, stimulates the expression of pro-Th2 cytokines (IL-25, IL-33, TSLP) that are required for the induction of food allergy by these cytokines; (3) egg allergy is suppressed in mouse models by the UPR inhibitor, metformin (a drug widely used to treat diabetes mellitus); and (4) metformin appears to have a protective effects in humans who have alpha-gal syndrome, which is a form of food allergy.
This presentation represents Panelists 3 and 4 as a joint presentation and This talk was the third panelist in the Health Equities and Disparities Session for the 4th Annual UC Data Day Conference hosted by UC Libraries.
Joint Talk with Dr. Pickle and Stef Murwsky – Title: Developing Best Practices to Address LGBTQ and Health Disparities
Sarah Pickle, MD (she/her/hers), Associate Professor, University of Cincinnati Department of Family and Community Medicine. Dr. Pickle and her colleagues are studying best practices for training future generations of health care professionals in transgender medicine. University of Cincinnati College of Medicine is one of the only US Medical Schools to have a nationally published, dedicated transgender medicine curriculum.
Stef Murawsky, MA, WGSS, Ph.D. Candidate, Sociology Pronouns: they/them/theirs
University of Cincinnati Department of Sociology
I am currently completing a qualitative dissertation that explores transgender patient experiences of navigating and managing a stigmatized gender identity in biomedical contexts. I plan to generate a critical analysis of stigma in healthcare that demonstrates how structural, interpersonal and individual level transgender healthcare experiences are gendered and racialized.
This talk was the second panelist in the Health Equities and Disparities Session for the 4th Annual UC Data Day Conference hosted by UC Libraries.
Tammy Mentzel, MPH, Assistant Director for Programs and Projects, University of Cincinnati, Academic Health Center, Cincinnati Cancer Center
Talk Title(s): Understanding Health Disparities and Perceptions of Discrimination in Greater Cincinnati
Tammy served as the Program Director for the Transformation of Mission-based Health Care through Diversity, Equity, and Inclusion project aimed at bolstering diversity in the health care workforce and eliminating health disparities in urban communities by identifying, testing and adopting evidence-based strategies and tools. Tammy was formerly in the College of Nursing at UC where she was a Research Associate and Program Director providing leadership and support on six funded research projects totaling over $4.6 million.
